Address for Correspondence: Juan Guzman Olea, Cardiologia Intervencionista, Clinica Cardiologica Rio Jamapa 5302 Jardines de San Manuel, Puebla, Mexico, Phone: +52 (551)4831640, +52(222)2275771
Juan Guzman Olea, Gabriel Guzman Olea
Interventional Cardiology Department, Clinica Cardiologica y Torre Medica Bioscan Puebla-Tlaxcala Mexico, Jardines de San Manuel, Puebla, Mexico
A 25-year-old male, without cardiovascular risk factors or cardiovascular history, was referred to our hospital for recurrent angina. Thirty days before he presented the signs of a clinical myocardial infarction without receiving medical assistance. An electrocardiogram showed a QS deflections and subepicardial ischemia in leads V1-V4 and qR deflection with subepicardial ischemia in leads DI-AVL (Fig. 1). Coronary angiography was performed that revealed a giant aneurysm of the left main coronary artery (Fig. 2A, arrow, Video 1), left anterior descending coronary artery with proximal lesion of 85% involving the origin of the 1st. diagonal branch Medina 0-1-1 (Fig. 2B, arrow, Video 2), codominant and ectatic circumflex and normal right coronary artery (Fig. 2C). Based on the findings and considering the age of the patient, we decided that myocardial viability should be evaluated and the patient should undergo surgical treatment.
The incidence of true coronary artery aneurysms is <1%. The right coronary artery is usually the most affected artery (40%) followed by the left anterior descending (32%), and the left main being the least affected artery (3.5%).(1) The presence of coronary aneurysm has been associated with poor long-term outcomes irrespective of the presence of concomitant atherosclerotic coronary artery disease. Clinical presentations range from incidental finding on cardiac imaging to acute coronary syndrome like this case (2, 3). Treatment options include medical therapy, surgical excision of aneurysm, coronary bypass surgery and percutaneous coronary interventions. However, the management of these patients poses a clinical dilemma to the physicians, due to the lack of evidence from randomized controlled trials or societal guideline recommendations (2, 3).
Figure 1. An electrocardiogram showing QS deflections and subepicardial ischemia in leads V1-V4 and qR deflection with subepicardial ischemia in leads DI-AVL
Figure 2. Coronary angiography views of a giant aneurysm of the left main coronary artery (A, arrow, Video 1- see videos at www.hvt-journal.com), left anterior descending coronary artery with proximal lesion of 85% involving the origin of the 1st. diagonal branch Medina 0-1-1 (B, arrow), codominant and ectatic circumflex and normal right coronary artery (C).
Video 1, 2. Coronary angiography views of a giant aneurysm of the left main coronary artery
Peer-review: Internal and External
Conflict of interest: None to declare
Authorship: J.G.O., G.G.O. are equally contributed to management of case
and preparation of article
Acknowledgement and funding: None to declare
Kanlikavak, Eskisehir, Turkey. Bulent Gorenek, Eskisehir, Turkey