Address for Correspondence: Ayan Abdrakhmanov,
Department of Interventional Arrhythmology, National Research Cardiac Surgery Centre, Astana, Kazakhstan
E-mail: ayan-3@mail.ru
A 14-year-old boy with Wolff-Parkinson-White syndrome underwent an electrophysiology study (EPs) for symptoms of palpitations and persistence of pre-excitation. He was detected to have right postero-septal or mid-septal accessory pathway on electrocardiogram ECG (Fig.1). Patient had no previous ablation and anti-arrhythmic therapy with amiodarone and beta-blockers were not effective. In a view of symptomatic palpitations in association with evidence of pre-excitation, he underwent an EPs (Fig.2). EPs performed under general anesthesia. 3D mapping of the heart with navigation system the Saint Jude Medical (SJM) Velocity identified an earliest accessory pathway (AP) potential in para-Hisian area (Fig. 3). AP effective refractory period was 235 ms, shortest pre-excited R-R interval (SPERRI) 225 ms, radiofrequency ablation was performed around para-Hisian area with low power (P-20-25W, t0C-50C) in postero-septal and mid-septal areas with no effect. The AP was too close to His bundle and we decided to perform cryoablation using created 3D anatomical map. During the cryomapping application (-30°) there was an effect (Fig. 4), after total cryoablation the pre-excitation disappeared (Fig. 5). In this case we used Medtronic cryocathether FreezorTM 7 Fr. Distal electrodes of the cryocathether were connected to the pin pad of navigation system SJM Velocity which allowed us to visualize the only tip of the cryocathether. The procedure was performed during the sinus rhythm with parameters: 240 sec, -420C. Cryoablation was successful with no complication. Adenosine test showed total atrioventricular (AV) block, which confirmed the effectiveness of the cryoablation (Fig. 6). The procedure lasted 97 minutes (from time of the puncture till the decannulation), no fluoroscopy was used. At 6-month follow-up, he continues to have no pre-excitation on ECG. Focal cryoablation of the para-Hisian AP can be safely performed in children to avoid AV block.
Peer-review: Internal
Conflict of interest: None to declare
Authorship: A.A., A.B., Z.E., A.T., O.N., A.B., S.B. equally contributed to management of case and preparation of report
Acknowledgement and funding: None to declare
Figure 1. Surface electrocardiogram: PQ- 100 ms, heart rate - 85 bpm, speed - 25 mm/s.
Figure 2. Electrogram and ECG tracing before ablation: 150 mm/s, PQ- 106 ms, AV- 76 ms.
AV – Atrioventricular, ECG- electrocardiogram
Figure 3. Focal cryoablation of para-Hisian AP. Navigation system SJM Velocity: yellow point – His, Red points – RF ablations, Blue point –cryoablation
AP – accessory pathway, AV – atrioventricular, CS- coronary sinus, IVC – inferior vena cava, RA – right atrium, RV – right ventricle, RF- radiofrequency, SVC – superior vena cava
Figure 4. Focal cryoablation of para-Hisian AP - cryomapping (-30°) application. PQ prolongation from 111 ms to 123 ms, 150 mm/s.
AP – accessory pathway
Figure 5. Focal cryoablation of para-Hisian AP. Effective cryoablation. PQ- 164 ms, AV- 140 ms, 150 mm/s.
AP – accessory pathway, AV – atrioventricular
Figure 6. Focal cryoablation of para-Hisian AP. Adenosine test. Drug induced total AV block, 150 mm/s.
AP – accessory pathway, AV – atrioventricular