A-7

Individual-typological features of regulation of cardiorhythm in foreign students during education process

Ainura M. Satarkulova, Shadiya Yu. Aisaeva, Almaz S. Shanazarov

Objective: In studies of the mechanisms of human adaptation to professional and educational activities, as well as in clinical practice, the method of mathematical analysis of heart rate variability (HRV) is widely used. Based on this, the aim of this paper is to determine the typology and characteristics of the vegetative regulation of the heart as a prenosological control of the functional state of the body of practically healthy foreign students.

Methods: In 2018, 389 male students from India and Pakistan, which are studying at the International higher school of medicine (ISM) aged 17-24, served as test subjects. For each student, the main HRV parameters were recorded in a sitting position for 5 minutes by means of “PSYCHOPHYSIOLOGIST” software and hardware company Medicom MTD  (Russia).

Results: In total, 52% of young men had type I (with a moderate predominance of central regulation), 5% - type II (with a pronounced predominance of central regulation), 36% - type III (with a moderate predominance of autonomous regulation), and 7% - type IV (with a pronounced predominance of autonomous regulation). Students with a predominance of central regulation (types I and II) compared with types III and IV (predominance of autonomous regulation) have an excess of sympathetic influences on the heart, as indicated by reliably low values ​​of the SDNN, Mo, TP and high level of SI, which leads to various dysfunctional disorders, especially with severe centralization. In the group of persons with type III, a balance is maintained between the tone of the sympathetic and parasympathetic nervous system, while type IV shows a significant prevalence of parasympathetic effects on the heart rhythm.

Conclusion: The results indicate a risk of developing disadaptation in the students' body during education process and the importance of systematic monitoring to detect early cardiac arrhythmias.

Key words: foreign students, heart rate variability, statistical and spectral characteristics, stress index, vegetative regulation.

A-8

Stent grafts implantation in patients with life-threatening aortic conditions – first experience in Kyrgyz Republic

Abdyldaev I.Z., Chevgun S.D., Aripov M.A., Bebezov I.H., Chukubaev M.A., Cholponbaev D. Ch., Nurbekov K.N., Daniyarov B.S., Toktosunova D.B.

Objective: Aortic diseases remain an acute and debatable problem. Among all the aortic pathologies, the most dangerous are dynamic aneurysmal expansion, traumatic dissections and / or aneurysms, pure aortic intima dissections. Contemporary and less invasive treatment method is the stent graft implantation into aorta.

This report describes the first experience of thoracic endovascular aortic repair (TEVAR) and endovascular aneurysm repair (EVAR) in the Kyrgyz Republic in consecutive patients with life-threatening aortic conditions.

Methods: Nine patients, who underwent TEVAR and EVAR, were presented after all clinical examinations, echocardiography and computed tomography angiography with various life-threatening aortic diseases. Among the pathologies there were 2 (22.2%) dissections only, traumatic aneurysm 1 (11.1%), aneurysm without dissection 1 (11.1%), aneurysm with intimal dissection 5 (55.6%). Seven patients with dissection had type B (The Stanford classification).

Results: TEVAR was performed in eight cases EVAR just in one. All patients reached the 6-month endpoint.  None of the following, such as aneurysm expansion, aneurysm thrombosis or a functioning of false lumen at the sites of the stent graft implantation have been recorded. In addition, no further progression of the false lumen below the implantation zones was visualized. Mean diameter of stent grafts was 31.4 ± 4.8 mm and  188.9 ± 34.6 mm in length.

Conclusion: This modest observation showed the effectiveness of stent grafts implantation procedures in various aortic life-threatening conditions, such as aneurysm and / or aortic intima dissection.

Key words: thoracic endovascular aortic repair (TEVAR), endovascular aneurism repair (EVAR), life-threatening aortic conditions, aortic aneurysm, aortic dissection, stent graft.