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EDITORIALS

COVID-19 and the cardiovascular system

The understanding of the pathophysiology of cardiovascular complications in COVID-19 is a key to the implementation of therapeutic measures, which may offer additional benefits, mainly for patients with severe disease, such as anticoagulants.

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CASE REPORT

Severe bradyarrhythmia requiring temporary pacemaker in a COVID-19 patient receiving lopinavir/ritonavir treatment: a case report

This case highlights it is necessary to investigate balance between efficacy and safety of lopinavir/ritonavir for COVID-19 therapy. Off –label prescribing lopinavir/ritonavir outside of a clinical trial setting should be avoided until the data have proven that treatment benefit over placebo.

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REVIEW

Athletic heart adaptation, pathological hypertrophy and sudden cardiac death

In this review, we aimed to represent recent physiological and clinical standpoints regarding to athletic heart syndrome as well as its difference from sedentary heart changes and pathological hypertrophy, its association with sudden cardiac death.

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ORIGINAL RESEARCH ARTICLE

Remodeling of the left heart in patients with rheumatic mitral valve disease after mitral valve replacement with preservation of subvalvular structures

This study shows the possibility of implanting the right size of the artificial heart valve, with rheumatic lesions of the mitral valve with the complete preservation of subvalvular structures.

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ORIGINAL RESEARCH ARTICLE

Atrial septal defect patients with greater shunts show susceptibility for ventricular arrhythmias

T wave peak-to-end interval is a measure of transmural dispersion of repolarization and accepted as a surrogate for increased ventricular arrhythmogenesis risk. Our findings show that ASD patients whose shunt ratio are ≥2.0 show increased risk for arrhythmias.

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REVIEW

Arrhythmias in COVID-19: clinical significance and management

Worldwide spread of coronavirus disease (COVID-19) caused overwhelming mortality rate during preceding half of the year 2020. Although coronavirus infection was known for mostly respiratory tract involvement, novel COVID-19 pandemic showed excessive cardiac mortality and arrhythmic complications. We aimed to summarize current literature and emphasize on underlying pathological mechanisms and global point of view to coronavirus and arrhythmia relationship.

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EDITORIALS

From Editor-in-Chief: Has everything changed during pandemic: peer-review, science, clinical practices and education, CV diseases?

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IMAGE

CT and MR images of cystic adventitial disease of the popliteal artery

Cystic adventitial disease (CAD) is a very rare vascular disorder with prevalence as low as 1:1000 of all vascular pathologies (1). This disease most frequently occurs in young or middle-aged male patients with male/female ratio of 5/1

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ORIGINAL RESEARCH ARTICLE

The effects of tocilizumab on clinical and laboratory features of patients with severe COVID-19: a single-center experience

Our observational study demonstrated significant improvement in oxygen saturation, reduction in inflammatory markers – leukocytosis, CRP and D-dimers and 83% recovery without need for mechanical ventilation and no mortality in patients with COVID-19 with severe multilobar bilateral pneumonia and CT score 3-4 receiving tocilizumab in addition to standard treatment.

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ORIGINAL RESEARCH ARTICLE

Assessment of cardiovascular risk in Kyrgyz Republic

An analysis of the current situation in the Kyrgyz Republic demonstrates that the areas of concern in care system for patients with cardiovascular diseases (CVD) are the insufficient and untimely identification of cardiovascular risk factors, as well as their ineffective management due to the incomplete implementation of existing risk stratification guidelines and decision-making. This study assesses distribution of total cardiovascular risk among the population of the Kyrgyz Republic using the WHO/ISH risk scale. In addition, the distribution of the main risk factors separately is calculated, as well as the frequency of some additional CVD risk factors that are not included into the WHO/ISH evaluation scale is estimated.

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CASE REPORT

Texidor’s twinge a rare cause of benign paroxysmal chest pain

Various maneuvers like lying down or sitting upright and attempting deep inspiration tends to help in such conditions. This case report is reporting an unusual presentation of this syndrome due to its long duration of episode than the duration described in the previous reports.

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CASE REPORT

Acute coronary syndrome, a rare manifestation of infective endocarditis: a case report

Presentation of an acute coronary syndrome related to infective endocarditis is rare but potentially lethal. For young people, acute myocardial infarction and an infection syndrome should lead us to suspect IE.

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